Mechanism exploration of Gouqi-wentang formula against type 2 diabetes mellitus by phytochemistry and network pharmacology-based analysis and biological validation

Mechanism exploration of Gouqi-wentang formula against type 2 diabetes mellitus by phytochemistry and network pharmacology-based analysis and biological validation

Abstract Background The Gouqi-wentang formula (GQWTF) is a herbal formula used by Academician Xiao-lin Tong for the clinical treatment of T2DM. GQWTF is beneficial to qi, nourishes Yin, clears heat, and promotes fluid production, but the effective components and their mechanism of action remain uncl...

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Bibliographic Details
Main Authors: Lin Han, Hao-yu Yang, Yu-jiao Zheng, Xiu-xiu Wei, Wen-chao Dan, Li-li Zhang, Qi-you Ding, Xu Ma, Xin-miao Wang, Lin-hua Zhao, Xiao-lin Tong
Format: Article
Language:English
Published: BMC 2021-09-01
Series:Chinese Medicine
Subjects:
T2DM
Gouqi-wentang formula (GQWTF)
LC–MS
Network pharmacology
Biological validation
Online Access:https://doi.org/10.1186/s13020-021-00479-2

Internet

https://doi.org/10.1186/s13020-021-00479-2

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