Validation of weak biological effects by round robin experiments: cytotoxicity/biocompatibility of SiO2 and polymer nanoparticles in HepG2 cells

Abstract All over the world, different types of nanomaterials with a diversified spectrum of applications are designed and developed, especially in the field of nanomedicine. The great variety of nanoparticles (NPs), in vitro test systems and cell lines led to a vast amount of publications with conf...

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Bibliographic Details
Main Authors: Lisa Landgraf, Daniel Nordmeyer, Peter Schmiel, Qi Gao, Sandra Ritz, Julia S. Gebauer, Stefan Graß, Silvia Diabaté, Lennart Treuel, Christina Graf, Eckart Rühl, Katharina Landfester, Volker Mailänder, Carsten Weiss, Reinhard Zellner, Ingrid Hilger
Format: Article
Language:English
Published: Nature Publishing Group 2017-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-02958-9