Inhibition of aldose reductase prevents experimental allergic airway inflammation in mice.

The bronchial asthma, a clinical complication of persistent inflammation of the airway and subsequent airway hyper-responsiveness, is a leading cause of morbidity and mortality in critically ill patients. Several studies have shown that oxidative stress plays a key role in initiation as well as ampl...

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Bibliographic Details
Main Authors: Umesh C S Yadav, Kota V Ramana, Leopoldo Aguilera-Aguirre, Istvan Boldogh, Hamid A Boulares, Satish K Srivastava
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-08-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2717330?pdf=render