NS1 specific CD8+ T-cells with effector function and TRBV11 dominance in a patient with parvovirus B19 associated inflammatory cardiomyopathy.

BACKGROUND: Parvovirus B19 (B19V) is the most commonly detected virus in endomyocardial biopsies (EMBs) from patients with inflammatory cardiomyopathy (DCMi). Despite the importance of T-cells in antiviral defense, little is known about the role of B19V specific T-cells in this entity. METHODOLOGY A...

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Bibliographic Details
Main Authors: Mathias Streitz, Michel Noutsias, Rudolf Volkmer, Maria Rohde, Gordon Brestrich, Andrea Block, Katrin Klippert, Katja Kotsch, Bernhard Ay, Michael Hummel, Uwe Kühl, Dirk Lassner, Heinz-Peter Schultheiss, Hans-Dieter Volk, Florian Kern
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2394660?pdf=render