Functional production of human antibody by the filamentous fungus Aspergillus oryzae

Functional production of human antibody by the filamentous fungus Aspergillus oryzae

Abstract Background Monoclonal antibodies (mAbs) as biopharmaceuticals take a pivotal role in the current therapeutic applications. Generally mammalian cell lines, such as those derived from Chinese hamster ovaries (CHO), are used to produce the recombinant antibody. However, there are still concern...

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Bibliographic Details
Main Authors: Hung Hiep Huynh, Naoki Morita, Toshihiro Sakamoto, Takuya Katayama, Takuya Miyakawa, Masaru Tanokura, Yasunori Chiba, Reiko Shinkura, Jun-ichi Maruyama
Format: Article
Language:English
Published: BMC 2020-05-01
Series:Fungal Biology and Biotechnology
Subjects:
Aspergillus oryzae
Antibody
Neutralization
Fc receptor
N-linked glycan
Online Access:http://link.springer.com/article/10.1186/s40694-020-00098-w

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http://link.springer.com/article/10.1186/s40694-020-00098-w

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