Secretory phospholipase A2 increases SR-BI-mediated selective uptake from HDL but not biliary cholesterol secretions⃞

High density lipoprotein cholesterol represents a major source of biliary cholesterol. Secretory phospholipase A2 (sPLA2) is an acute phase enzyme mediating decreased plasma HDL cholesterol levels. Clinical studies reported a link between increased sPLA2 expression and the presence of cholesterol ga...

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Bibliographic Details
Main Authors: Uwe J.F. Tietge, Niels Nijstad, Rick Havinga, Julius F.W. Baller, Fjodor H. van der Sluijs, Vincent W. Bloks, Thomas Gautier, Folkert Kuipers
Format: Article
Language:English
Published: Elsevier 2008-03-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520424149