Rpn11-mediated ubiquitin processing in an ancestral archaeal ubiquitination system

Ubiquitin modification also occurs in archaea. Here, the authors characterize an archaeal ancestral ubiquitination system, present the crystal structure of the archaeal deubiquitinase Rpn11 from Caldiarchaeum subterraneum bound to ubiquitin and provide insights into evolutionary relationships.

Bibliographic Details
Main Authors: Adrian C. D. Fuchs, Lorena Maldoner, Matthias Wojtynek, Marcus D. Hartmann, Jörg Martin
Format: Article
Language:English
Published: Nature Publishing Group 2018-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-05198-1