SIX1 Activation Is Involved in Cell Proliferation, Migration, and Anti-inflammation of Acute Ischemia/Reperfusion Injury in Mice

SIX1 Activation Is Involved in Cell Proliferation, Migration, and Anti-inflammation of Acute Ischemia/Reperfusion Injury in Mice

Nephrogenic proteins are re-expressed after ischemia/reperfusion (I/R) injury; however, the role of these proteins is still unknown. We found that sine oculis homeobox 1 (SIX1), a developmentally regulated homeoprotein, is reactivated in tubular epithelial cells after I/R injury associated with cell...

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Bibliographic Details
Main Authors: Yong Jin, Manling Zhang, Meishuang Li, Hong Zhang, Lihua Zhao, Cheng Qian, Shensen Li, Hao Zhang, Min Gao, Binbin Pan, Rongfeng Li, Xin Wan, Changchun Cao
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Molecular Biosciences
Subjects:
ischemia/reperfusion
sine oculis homeobox 1
tubular epithelial cells
monocytes/macrophages
nuclear factor-κB
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2021.725319/full

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https://www.frontiersin.org/articles/10.3389/fmolb.2021.725319/full

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