On the Pharmacology of Farnesoid X Receptor Agonists: Give me an “A”, Like in “Acid”

The Farnesoid X Receptor (FXR) has recently moved into the spotlight through the release of clinical data using Obeticholic Acid, an FXR agonist, that demonstrated effectiveness of this bile acid-like drug in patients with Primary Biliary Cirrhosis and Non-alcoholic Steatohepatitis (NASH). FXR holds...

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Bibliographic Details
Main Authors: Eva Hambruch, Olaf Kinzel, Claus Kremoser
Format: Article
Language:English
Published: KenzPub 2016-06-01
Series:Nuclear Receptor Research
Subjects:
Online Access:http://www.kenzpub.com/journals/nurr/2016/101207/