Chronic Intermittent Hypobaric Hypoxia Decreases High Blood Pressure by Stabilizing the Vascular Renin-Angiotensin System in Spontaneously Hypertensive Rats

Chronic Intermittent Hypobaric Hypoxia Decreases High Blood Pressure by Stabilizing the Vascular Renin-Angiotensin System in Spontaneously Hypertensive Rats

Background and AimsPrevious studies have demonstrated the anti-hypertensive effect of chronic intermittent hypobaric hypoxia (CIHH) in hypertensive rats. The present study investigated the anti-hypertensive effect of CIHH in spontaneously hypertensive rats (SHR) and the role of the renin-angiotensin...

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Bibliographic Details
Main Authors: Hua Chen, Bin Yu, Xinqi Guo, Hong Hua, Fang Cui, Yue Guan, Yanming Tian, Xiangjian Zhang, Yi Zhang, Huijie Ma
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Physiology
Subjects:
chronic intermittent hypobaric hypoxia
anti-hypertension
endothelial-dependent relaxation
renin-angiotensin system
Ang II
Ang1-7
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.639454/full

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https://www.frontiersin.org/articles/10.3389/fphys.2021.639454/full

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