An alternative microRNA-mediated post-transcriptional regulation of GADD45A by p53 in human non-small-cell lung cancer cells

Abstract GADD45A (growth arrest and DNA damage inducible alpha), a stress response gene induced by genotoxic and nongenotoxic stresses, is implicated in various key processes, including the control of cell cycle checkpoints and DNA repair. The expression of GADD45A is directly regulated by numerous...

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Bibliographic Details
Main Authors: Jie Li, Jie Dong, Shaohua Li, Wei Xia, Xueting Su, Xingliang Qin, Ying Chen, Hongmei Ding, Hui Li, Aixue Huang, Chenjun Bai, Tongnan Hu, Chenglong Wang, Bingfeng Chu, Ningsheng Shao
Format: Article
Language:English
Published: Nature Publishing Group 2017-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-07332-3