BNIP3 in Lung Cancer: To Kill or Rescue?

Bcl-2/adenovirus E1B 19kDa interacting protein 3 (BNIP3) is a pro-apoptotic BH3-only protein of the Bcl-2 family. Initially, BNIP3 was described as one of the mediators of hypoxia-induced apoptotic cell death in cardiac myocytes and neurons. Besides apoptosis, BNIP3 plays a crucial role in autophagy...

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Bibliographic Details
Main Authors: Anna S. Gorbunova, Maria A. Yapryntseva, Tatiana V. Denisenko, Boris Zhivotovsky
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/12/11/3390