Involvement of Chromatin Remodeling Genes and the Rho GTPases RhoB and CDC42 in Ovarian Clear Cell Carcinoma

Involvement of Chromatin Remodeling Genes and the Rho GTPases RhoB and CDC42 in Ovarian Clear Cell Carcinoma

ObjectiveOvarian clear cell carcinomas (OCCCs) constitute a rare ovarian cancer subtype with distinct clinical features, but may nonetheless be difficult to distinguish morphologically from other subtypes. There is limited knowledge of genetic events driving OCCC tumorigenesis beyond ARID1A, which i...

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Bibliographic Details
Main Authors: Nicolai Skovbjerg Arildsen, Jenny-Maria Jönsson, Katarina Bartuma, Anna Ebbesson, Sofia Westbom-Fremer, Anna Måsbäck, Susanne Malander, Mef Nilbert, Ingrid A. Hedenfalk
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-05-01
Series:Frontiers in Oncology
Subjects:
clear cell ovarian cancer
gene expression profiling
deep sequencing
inter-tumor heterogeneity
chromatin modification
Rho GTPase
Online Access:http://journal.frontiersin.org/article/10.3389/fonc.2017.00109/full

Internet

http://journal.frontiersin.org/article/10.3389/fonc.2017.00109/full

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