Additive effects of physical exercise and environmental enrichment on adult hippocampal neurogenesis in mice

Additive effects of physical exercise and environmental enrichment on adult hippocampal neurogenesis in mice

Voluntary physical exercise (wheel running, RUN) and environmental enrichment (ENR) both stimulate adult hippocampal neurogenesis but do so by different mechanisms. RUN induces precursor cell proliferation, whereas ENR exerts a survival-promoting effect on newborn cells. In addition, continued RUN p...

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Bibliographic Details
Main Authors: Klaus Fabel, Susanne Wolf, Dan Ehninger, Harish Babu, Perla Galicia, Gerd Kempermann
Format: Article
Language:English
Published: Frontiers Media S.A. 2009-11-01
Series:Frontiers in Neuroscience
Subjects:
Hippocampus
Learning
precursor cell
reserve
Online Access:http://journal.frontiersin.org/Journal/10.3389/neuro.22.002.2009/full

Internet

http://journal.frontiersin.org/Journal/10.3389/neuro.22.002.2009/full

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