IL-1Ra (recombinant human IL-1 receptor antagonist) in the treatment of rheumatoid arthritis: the efficacy

Interleukin 1 receptor antagonist (IL-1Ra) is a naturally occurring IL-1 inhibitor, acting as a “receptor antagonist”, which blocks IL-1 mediated signal transduction. In 1990 IL-1Ra was cloned and later on, a large numbers of studies led to disclosure of the crucial importance of the imbalance betwe...

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Bibliographic Details
Main Authors: L. Cozzi, M. Vezzù, U. Fiocco, S. Todesco
Format: Article
Language:English
Published: PAGEPress Publications 2011-09-01
Series:Reumatismo
Online Access:http://www.reumatismo.org/index.php/reuma/article/view/190