KCa3.1 Transgene Induction in Murine Intestinal Epithelium Causes Duodenal Chyme Accumulation and Impairs Duodenal Contractility

KCa3.1 Transgene Induction in Murine Intestinal Epithelium Causes Duodenal Chyme Accumulation and Impairs Duodenal Contractility

Abstract: The epithelial intermediate-conductance calcium/calmodulin-regulated KCa3.1 channel is considered to be a regulator of intestine function by controlling chloride secretion and water/salt balance. Yet, little is known about the functional importance of KCa3.1 in the intestinal epithelium in...

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Bibliographic Details
Main Authors: Marta Sofía Valero, Mariano Ramón-Gimenez, Javier Lozano-Gerona, Pablo Delgado-Wicke, Pilar Calmarza, Aida Oliván-Viguera, Víctor López, Ángel-Luis Garcia-Otín, Salvador Valero, Esther Pueyo, Kirk L. Hamilton, Hiroto Miura, Ralf Köhler
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:International Journal of Molecular Sciences
Subjects:
intermediate-conductance calcium-activated potassium channel
KCa3.1
epithelium
duodenum
contractility
transgenic mice
Online Access:http://www.mdpi.com/1422-0067/20/5/1193

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http://www.mdpi.com/1422-0067/20/5/1193

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