Application of Nanopharmaceutics for Flibanserin Brain Delivery Augmentation Via the Nasal Route

Application of Nanopharmaceutics for Flibanserin Brain Delivery Augmentation Via the Nasal Route

Flibanserin (FLB) is a nonhormonal medicine approved by the Food and Drug Administration (FDA) to treat the hypoactive sexual appetite disorder in females. However, the peroral administration of the medicine is greatly affected by its poor bioavailability as a result of its extensive first-pass effe...

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Bibliographic Details
Main Authors: Osama A. A. Ahmed, Usama A. Fahmy, Shaimaa M. Badr-Eldin, Hibah M. Aldawsari, Zuhier A. Awan, Hani Z. Asfour, Ahmed K. Kammoun, Giuseppe Caruso, Filippo Caraci, Anas Alfarsi, Raniyah A. Al-Ghamdi, Rawan A. Al-Ghamdi, Nabil A. Alhakamy
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Nanomaterials
Subjects:
flibanserin
transfersomes
hydrogel
ex vivo permeation
in vivo pharmacokinetics
Online Access:https://www.mdpi.com/2079-4991/10/7/1270

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https://www.mdpi.com/2079-4991/10/7/1270

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