Lentiviral Mediating Genetic Engineered Mesenchymal Stem Cells for Releasing IL-27 as a Gene Therapy Approach for Autoimmune Diseases

Lentiviral Mediating Genetic Engineered Mesenchymal Stem Cells for Releasing IL-27 as a Gene Therapy Approach for Autoimmune Diseases

Objective: Autoimmune diseases precede a complex dysregulation of the immune system. T helper17 (Th17) and interleukin (IL)-17 have central roles in initiation of inflammation and subsequent autoimmune diseases. IL-27 significantly controls autoimmune diseases by Th17 and IL-17 suppression. In th...

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Bibliographic Details
Main Authors: Shohreh Hajizadeh-Sikaroodi, Ahmad Hosseini, Ali Falla, Hajar Estiri, Zahra Noormohammadi, Mohammad Salehi, Sayyed Mohammad Hossein Ghaderian, Haleh Akhavan Niaki, Masoud Soleimani, Bahram Kazemi
Format: Article
Language:English
Published: Royan Institute (ACECR), Tehran 2014-04-01
Series:Cell Journal
Subjects:
Autoimmune Disease
Gene Therapy
IL-27
Mesenchymal Stem Cells
Online Access:http://celljournal.org/library/upload/article/af_25234445425447253433253326544324527635323-Shohreh%20Hajizadeh-1-1-phone.pdf

Internet

http://celljournal.org/library/upload/article/af_25234445425447253433253326544324527635323-Shohreh%20Hajizadeh-1-1-phone.pdf

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