Efficacy of Immune Checkpoint Inhibitors in Upper Tract Urothelial Carcinomas: Current Knowledge and Future Directions

Upper tract urothelial carcinoma (UTUC) represents a rare and aggressive malignancy arising from the renal pelvis or ureter. It can develop sporadically or have a hereditary origin, such as Lynch syndrome, caused by DNA mismatch repair deficiency, leading to microsatellite instability phenotype. Acc...

Full description

Bibliographic Details
Main Authors: Jonathan Thouvenin, Nieves Martínez Chanzá, Omar Alhalabi, Hervé Lang, Nizar M. Tannir, Philippe Barthélémy, Gabriel G. Malouf
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/13/17/4341