Positive selection results in frequent reversible amino acid replacements in the G protein gene of human respiratory syncytial virus.

Human respiratory syncytial virus (HRSV) is the major cause of lower respiratory tract infections in children under 5 years of age and the elderly, causing annual disease outbreaks during the fall and winter. Multiple lineages of the HRSVA and HRSVB serotypes co-circulate within a single outbreak an...

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Bibliographic Details
Main Authors: Viviane F Botosso, Paolo M de A Zanotto, Mirthes Ueda, Eurico Arruda, Alfredo E Gilio, Sandra E Vieira, Klaus E Stewien, Teresa C T Peret, Leda F Jamal, Maria I de M C Pardini, João R R Pinho, Eduardo Massad, Osvaldo A Sant'anna, Eddie C Holmes, Edison L Durigon, VGDN Consortium
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19119418/pdf/?tool=EBI