No Adaptation of the Prion Strain in a Heterozygous Case of Variant Creutzfeldt-Jakob Disease

No Adaptation of the Prion Strain in a Heterozygous Case of Variant Creutzfeldt-Jakob Disease

We investigated a clinical case of variant Creutzfeldt-Jakob Disease in a person heterozygous for methionine/valine at codon 129 of the prion protein gene and identified the same strain properties in variant Creutzfeldt-Jakob disease in methionine homozygous persons and in bovine spongiform encephal...

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Bibliographic Details
Main Authors: Aileen Boyle, Chris Plinston, Fraser Laing, Graeme Mackenzie, Robert G. Will, Jean C. Manson, Abigail B. Diack
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2020-06-01
Series:Emerging Infectious Diseases
Subjects:
Bovine spongiform encephalopathy
prions and related diseases
strain
variant Creutzfeldt-Jakob disease
transmissible spongiform encephalopathy
zoonoses
Online Access:https://wwwnc.cdc.gov/eid/article/26/6/19-1116_article

Internet

https://wwwnc.cdc.gov/eid/article/26/6/19-1116_article

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