Mechanisms of organelle biogenesis govern stochastic fluctuations in organelle abundance

Mechanisms of organelle biogenesis govern stochastic fluctuations in organelle abundance

Fluctuations in organelle abundance can profoundly limit the precision of cell biological processes from secretion to metabolism. We modeled the dynamics of organelle biogenesis and predicted that organelle abundance fluctuations depend strongly on the specific mechanisms that increase or decrease t...

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Bibliographic Details
Main Authors: Shankar Mukherji, Erin K O'Shea
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2014-06-01
Series:eLife
Subjects:
systems biology
organelles
mathematical modeling
fluctuation
cell biology
Online Access:https://elifesciences.org/articles/02678

Internet

https://elifesciences.org/articles/02678

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