Somatic mutation patterns and compound response in cancers

The use of various cancer cell lines can recapitulate knowntumor-associated mutations and genetically define cancersubsets. This approach also enables comparative surveys ofassociations between cancer mutations and drug responses.Here, we analyzed the effects of ∼40,000 compounds oncancer cell lines...

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Bibliographic Details
Main Authors: Ningning He, Nayoung Kim, Sukjoon Yoon
Format: Article
Language:English
Published: Korean Society for Biochemistry and Molecular Biology 2013-02-01
Series:BMB Reports
Subjects:
Online Access:http://bmbreports.org/jbmb/pdf.php?data=MTMwOTI2MTdAcGRmX3JhaW50cmFjZV9sZWV5c0AlNUI0Ni0yJTVEMTMwMjI2MTg0NF8lMjgwOTctMTAyJTI5Qk1CXzEyLTIyNi5wZGY=