Magnolol Enhances the Therapeutic Effects of TRAIL through DR5 Upregulation and Downregulation of c-FLIP and Mcl-1 Proteins in Cancer Cells

Magnolol is a biologically active compound, isolated from the Chinese herb <i>Magnolia</i>, that regulates antiproliferative, anticancer, antiangiogenic and antimetastatic activities. We found that magnolol sensitizes TRAIL-induced apoptotic cell death via upregulation of DR5 and downreg...

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Bibliographic Details
Main Authors: Seon Min Woo, Kyoung-jin Min, Taeg Kyu Kwon
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Molecules
Subjects:
DR5
Online Access:https://www.mdpi.com/1420-3049/25/19/4591