Genetic Dissection of Cardiac Remodeling in an Isoproterenol-Induced Heart Failure Mouse Model.

Genetic Dissection of Cardiac Remodeling in an Isoproterenol-Induced Heart Failure Mouse Model.

We aimed to understand the genetic control of cardiac remodeling using an isoproterenol-induced heart failure model in mice, which allowed control of confounding factors in an experimental setting. We characterized the changes in cardiac structure and function in response to chronic isoproterenol in...

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Bibliographic Details
Main Authors: Jessica Jen-Chu Wang, Christoph Rau, Rozeta Avetisyan, Shuxun Ren, Milagros C Romay, Gabriel Stolin, Ke Wei Gong, Yibin Wang, Aldons J Lusis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-07-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4934852?pdf=render

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http://europepmc.org/articles/PMC4934852?pdf=render

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