Cholinergic Neurons - Keeping Check on Amyloid beta in the Cerebral Cortex

The physiological relevance of the uptake of ligands with no apparent trophic functions via the p75 neurotrophin receptor (p75NTR) remains unclear. Herein, we propose a homeostatic role for this in clearance of amyloid β (Aβ) in the brain. We hypothesize that uptake of A&am...

Full description

Bibliographic Details
Main Authors: Saak V. Ovsepian, Jochen eHerms
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-12-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2013.00252/full