Thromboxane-Dependent Platelet Activation in Obese Subjects with Prediabetes or Early Type 2 Diabetes: Effects of Liraglutide- or Lifestyle Changes-Induced Weight Loss

Thromboxane-Dependent Platelet Activation in Obese Subjects with Prediabetes or Early Type 2 Diabetes: Effects of Liraglutide- or Lifestyle Changes-Induced Weight Loss

Thromboxane (TX)-dependent platelet activation and lipid peroxidation, as reflected in vivo by the urinary excretion of 11-dehydro-TXB<sub>2</sub> and 8-iso-prostaglandin (PG)F<sub>2&#945;</sub>, play a key role in atherothrombosis in obesity and type 2 diabetes mellitus...

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Bibliographic Details
Main Authors: Paola Simeone, Rossella Liani, Romina Tripaldi, Augusto Di Castelnuovo, Maria Teresa Guagnano, Armando Tartaro, Riccardo C. Bonadonna, Virginia Federico, Francesco Cipollone, Agostino Consoli, Francesca Santilli
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Series:Nutrients
Subjects:
obesity
diabetes mellitus
weight loss
oxidative stress
platelet activation
adipose tissue distribution
liraglutide
Online Access:https://www.mdpi.com/2072-6643/10/12/1872

Internet

https://www.mdpi.com/2072-6643/10/12/1872

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