Naturally Inspired Molecules as Multifunctional Agents for Alzheimer’s Disease Treatment

Naturally Inspired Molecules as Multifunctional Agents for Alzheimer’s Disease Treatment

Alzheimer’s disease (AD) has been defined as a multi-factorial disorder resulting from a complex array of networked cellular and molecular mechanisms. In particular, elevated levels of Aβ protein and its aggregation products in the presence of metal ions proved to be highly neurotoxic and therapeuti...

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Bibliographic Details
Main Authors: Angela Rampa, Andrea Tarozzi, Francesca Mancini, Letizia Pruccoli, Rita Maria Concetta Di Martino, Silvia Gobbi, Alessandra Bisi, Angela De Simone, Francesco Palomba, Nelsi Zaccheroni, Federica Belluti
Format: Article
Language:English
Published: MDPI AG 2016-05-01
Series:Molecules
Subjects:
AD
BACE-1
benzophenone
chalcone
metal chelation
natural products
Reactive oxygen species
Online Access:http://www.mdpi.com/1420-3049/21/5/643

Internet

http://www.mdpi.com/1420-3049/21/5/643

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