Chemoresistance in H-Ferritin Silenced Cells: The Role of NF-κB

Chemoresistance in H-Ferritin Silenced Cells: The Role of NF-κB

Nuclear Factor-κB (NF-κB) is frequently activated in tumor cells contributing to aggressive tumor growth and resistance to chemotherapy. Here we demonstrate that Ferritin Heavy Chain (FHC) protein expression inversely correlates with NF-κB activation in cancer cell line...

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Bibliographic Details
Main Authors: Ilenia Aversa, Roberta Chirillo, Emanuela Chiarella, Fabiana Zolea, Maddalena Di Sanzo, Flavia Biamonte, Camillo Palmieri, Francesco Costanzo
Format: Article
Language:English
Published: MDPI AG 2018-09-01
Series:International Journal of Molecular Sciences
Subjects:
Ferritin Heavy Chain
NF-κB
ROS
chemoresistance
Online Access:http://www.mdpi.com/1422-0067/19/10/2969

Internet

http://www.mdpi.com/1422-0067/19/10/2969

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