Modulation of microRNA activity by semi-microRNAs (smiRNAs)

Modulation of microRNA activity by semi-microRNAs (smiRNAs)

The ribonuclease Dicer plays a central role in the microRNA pathway by catalyzing the formation of 19 to 24-nucleotide (nt) long microRNAs. Subsequently incorporated into Ago2 effector complexes, microRNAs are known to regulate messenger RNA (mRNA) translation. Whether shorter RNA species derived fr...

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Bibliographic Details
Main Authors: Isabelle ePlante, Hélène ePlé, Patricia eLandry, Preethi Herat Gunaratne, Patrick eProvost
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-06-01
Series:Frontiers in Genetics
Subjects:
microRNA
non-coding RNA
dicer
Argonaute 2
RNA silencing
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2012.00099/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fgene.2012.00099/full

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