Differential involvement of corticospinal tract (CST) fibers in UMN-predominant ALS patients with or without CST hyperintensity: A diffusion tensor tractography study

Diagnosis of amyotrophic lateral sclerosis (ALS) depends on clinical evidence of combined upper motor neuron (UMN) and lower motor neuron (LMN) degeneration, although ALS patients can present with features predominantly of one or the other. Some UMN-predominant patients show hyperintense signal alon...

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Bibliographic Details
Main Authors: Venkateswaran Rajagopalan, Erik P. Pioro
Format: Article
Language:English
Published: Elsevier 2017-01-01
Series:NeuroImage: Clinical
Subjects:
DTI
ALS
Online Access:http://www.sciencedirect.com/science/article/pii/S2213158217300517