Molecular Choreography and Structure of Ca<sup>2+</sup> Release-Activated Ca<sup>2+</sup> (CRAC) and K<sub>Ca2+</sub> Channels and Their Relevance in Disease with Special Focus on Cancer

Molecular Choreography and Structure of Ca<sup>2+</sup> Release-Activated Ca<sup>2+</sup> (CRAC) and K<sub>Ca2+</sub> Channels and Their Relevance in Disease with Special Focus on Cancer

Ca<sup>2+</sup> ions play a variety of roles in the human body as well as within a single cell. Cellular Ca<sup>2+</sup> signal transduction processes are governed by Ca<sup>2+</sup> sensing and Ca<sup>2+</sup> transporting proteins. In this review, we...

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Bibliographic Details
Main Authors: Adéla Tiffner, Isabella Derler
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Membranes
Subjects:
STIM1
Orai1
CRAC channels
store-operated channel activation (SOCE), Ca<sup>2+</sup>-activated K<sup>+</sup> channels (K<sub>Ca2+</sub>), SK3
SK3-Orai1 interplay
Online Access:https://www.mdpi.com/2077-0375/10/12/425

Internet

https://www.mdpi.com/2077-0375/10/12/425

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