Intrauterine Zika virus infection of pregnant immunocompetent mice models transplacental transmission and adverse perinatal outcomes

Zika virus infection of pregnant women is associated with congenital neurological disorders. Here, Vermillionet al. develop an immunocompetent mouse model for identification of factors at the maternal-fetal interface that contribute to adverse perinatal outcomes.

Bibliographic Details
Main Authors: Meghan S. Vermillion, Jun Lei, Yahya Shabi, Victoria K. Baxter, Nathan P. Crilly, Michael McLane, Diane E. Griffin, Andrew Pekosz, Sabra L. Klein, Irina Burd
Format: Article
Language:English
Published: Nature Publishing Group 2017-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms14575