Two functional variants of IRF5 influence the development of macular edema in patients with non-anterior uveitis.

Two functional variants of IRF5 influence the development of macular edema in patients with non-anterior uveitis.

OBJECTIVE:Interferon (IFN) signaling plays a crucial role in autoimmunity. Genetic variation in interferon regulatory factor 5 (IRF5), a major regulator of the type I interferon induction, has been associated with risk of developing several autoimmune diseases. In the current study we aimed to evalu...

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Main Authors: Ana Márquez, María Carmen Cénit, Miguel Cordero-Coma, Norberto Ortego-Centeno, Alfredo Adán, Alejandro Fonollosa, David Díaz Valle, Esperanza Pato, Ricardo Blanco, Joaquín Cañal, Manuel Díaz-Llopis, Enrique de Ramón, María José Del Rio, José Luis García Serrano, Joseba Artaraz, José Manuel Martín-Villa, Víctor Llorenç, Marina Begoña Gorroño-Echebarría, Javier Martín
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3792064?pdf=render

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http://europepmc.org/articles/PMC3792064?pdf=render

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