Dual exon skipping in myostatin and dystrophin for Duchenne muscular dystrophy

<p>Abstract</p> <p>Background</p> <p>Myostatin is a potent muscle growth inhibitor that belongs to the Transforming Growth Factor-β (TGF-β) family. Mutations leading to non functional myostatin have been associated with hypermuscularity in several organisms. By contrast...

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Main Authors: van Ommen Gert Jan B, den Dunnen Johan T, de Gorter David JJ, Terlouw Samuel, van Heiningen Sandra H, Hoogaars Willem MH, Kemaladewi Dwi U, Aartsma-Rus Annemieke, ten Dijke Peter, 't Hoen Peter AC
Format: Article
Language:English
Published: BMC 2011-04-01
Series:BMC Medical Genomics
Online Access:http://www.biomedcentral.com/1755-8794/4/36