Bone Marrow-Derived Mesenchymal Stem Cells and Their Conditioned Medium Attenuate Fibrosis in an Irreversible Model of Unilateral Ureteral Obstruction

Bone Marrow-Derived Mesenchymal Stem Cells and Their Conditioned Medium Attenuate Fibrosis in an Irreversible Model of Unilateral Ureteral Obstruction

The therapeutic potential of mesenchymal stem cells (MSCs) and their conditioned medium (MSC-CM) has been extensively studied. MSCs can repair tissue, reduce local inflammation, and modulate the immune response. Persistent renal tubular interstitial inflammation results in fibrosis and leads to chro...

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Bibliographic Details
Main Authors: Andrei F. Da Silva, Kleiton Silva, Luciana A. Reis, Vicente P. C. Teixeira, Nestor Schor
Format: Article
Language:English
Published: SAGE Publishing 2015-12-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/096368915X687534

Internet

https://doi.org/10.3727/096368915X687534

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