Biomarkers for Duchenne muscular dystrophy: myonecrosis, inflammation and oxidative stress

Biomarkers for Duchenne muscular dystrophy: myonecrosis, inflammation and oxidative stress

Duchenne muscular dystrophy (DMD) is a lethal, X-linked disease that causes severe loss of muscle mass and function in young children. Promising therapies for DMD are being developed, but the long lead times required when using clinical outcome measures are hindering progress. This progress would be...

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Bibliographic Details
Main Authors: Miranda D. Grounds, Jessica R. Terrill, Basma A. Al-Mshhdani, Marisa N. Duong, Hannah G. Radley-Crabb, Peter G. Arthur
Format: Article
Language:English
Published: The Company of Biologists 2020-02-01
Series:Disease Models & Mechanisms
Subjects:
dmd
dystrophic mice
rats
dogs
biomarkers
blood
urine
muscle necrosis
inflammation
neutrophils
oxidative stress
Online Access:http://dmm.biologists.org/content/13/2/dmm043638

Internet

http://dmm.biologists.org/content/13/2/dmm043638

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