Succinate overproduction: A case study of computational strain design using a comprehensive Escherichia coli kinetic model

Computational strain design prediction accuracy has been the focus for many recent efforts through the selective integration of kinetic information into metabolic models. In general, kinetic model prediction quality is determined by the range and scope of genetic and/or environmental perturbations u...

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Bibliographic Details
Main Authors: Ali eKhodayari, Anupam eChowdhury, Costas D Maranas
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-01-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fbioe.2014.00076/full