Succinate overproduction: A case study of computational strain design using a comprehensive Escherichia coli kinetic model
Computational strain design prediction accuracy has been the focus for many recent efforts through the selective integration of kinetic information into metabolic models. In general, kinetic model prediction quality is determined by the range and scope of genetic and/or environmental perturbations u...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2015-01-01
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Series: | Frontiers in Bioengineering and Biotechnology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fbioe.2014.00076/full |