HIV and HCV augments inflammatory responses through increased TREM-1 expression and signaling in Kupffer and Myeloid cells.

HIV and HCV augments inflammatory responses through increased TREM-1 expression and signaling in Kupffer and Myeloid cells.

Chronic infection with human immunodeficiency virus (HIV) and hepatitis C virus (HCV) affects an estimated 35 million and 75 million individuals worldwide, respectively. These viruses induce persistent inflammation which often drives the development or progression of organ-specific diseases and even...

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Bibliographic Details
Main Authors: Jinhee Hyun, Robert S McMahon, Anna L Lang, Jasmine S Edwards, Alejandro Dmitar Badilla, Morgan E Greene, Geoffrey W Stone, Suresh Pallikkuth, Mario Stevenson, Derek M Dykxhoorn, Shyam Kottilil, Savita Pahwa, Emmanuel Thomas
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-07-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1007883

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https://doi.org/10.1371/journal.ppat.1007883

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