Regulation of sterol carrier protein gene expression by the Forkhead transcription factor FOXO3a

The SCP gene encodes two proteins, sterol carrier protein X (SCPx) and SCP2, that are independently regulated by separate promoters. SCPx has been shown to be the thiolase involved in the breakdown of branched-chain fatty acids and in the biosynthesis of bile acids. The in vivo function of SCP2 howe...

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Main Authors: Tobias B. Dansen, Geert J.P.L. Kops, Simone Denis, Nannette Jelluma, Ronald J.A. Wanders, Johannes L. Bos, Boudewijn M.T. Burgering, Karel W.A. Wirtz
Format: Article
Language:English
Published: Elsevier 2004-01-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520319234