Sestrin2 Attenuates Cellular Senescence by Inhibiting NADPH Oxidase 4 Expression
Background Sestrin2 (Sesn2) is involved in the maintenance of metabolic homeostasis and aging via modulation of the 5' AMP-activated protein kinase-mammalian target of rapamycin (AMPK-mTOR) pathway. Methods Wild-type and Sesn2 knockout (KO) mice of the 129/SvJ background were maintained in a pa...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Korea Geriatrics Society
2020-12-01
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| Series: | Annals of Geriatric Medicine and Research |
| Subjects: | |
| Online Access: | http://www.e-agmr.org/upload/pdf/agmr-20-0051.pdf |