Sestrin2 Attenuates Cellular Senescence by Inhibiting NADPH Oxidase 4 Expression
Background Sestrin2 (Sesn2) is involved in the maintenance of metabolic homeostasis and aging via modulation of the 5' AMP-activated protein kinase-mammalian target of rapamycin (AMPK-mTOR) pathway. Methods Wild-type and Sesn2 knockout (KO) mice of the 129/SvJ background were maintained in a pa...
Main Authors: | Chae Young Hwang, Ying-Hao Han, Seung-Min Lee, Sang-Mi Cho, Dae-Yeul Yu, Ki-Sun Kwon |
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Format: | Article |
Language: | English |
Published: |
Korea Geriatrics Society
2020-12-01
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Series: | Annals of Geriatric Medicine and Research |
Subjects: | |
Online Access: | http://www.e-agmr.org/upload/pdf/agmr-20-0051.pdf |
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