Immediate and delayed cochlear neuropathy after noise exposure in pubescent mice.

Moderate acoustic overexposure in adult rodents is known to cause acute loss of synapses on sensory inner hair cells (IHCs) and delayed degeneration of the auditory nerve, despite the completely reversible temporary threshold shift (TTS) and morphologically intact hair cells. Our objective was to de...

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Bibliographic Details
Main Authors: Jane Bjerg Jensen, Andrew C Lysaght, M Charles Liberman, Klaus Qvortrup, Konstantina M Stankovic
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0125160