The Tumor Microenvironment in the Response to Immune Checkpoint Blockade Therapies

Tumor cells constantly interact with their microenvironment, which comprises a variety of immune cells together with endothelial cells and fibroblasts. The composition of the tumor microenvironment (TME) has been shown to influence response to immune checkpoint blockade (ICB). ICB takes advantage of...

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Bibliographic Details
Main Authors: Florent Petitprez, Maxime Meylan, Aurélien de Reyniès, Catherine Sautès-Fridman, Wolf H. Fridman
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00784/full