N-carbamylglutamate restores nitric oxide synthesis and attenuates high altitude-induced pulmonary hypertension in Holstein heifers ascended to high altitude

N-carbamylglutamate restores nitric oxide synthesis and attenuates high altitude-induced pulmonary hypertension in Holstein heifers ascended to high altitude

Abstract Background High-altitude pulmonary hypertension (HAPH) is a life-threating condition for animals in high altitude, and disturbance of endothelial nitric oxide (NO) synthesis contributes to its pathogenesis. N-carbamylglutamate (NCG), which enhances arginine synthesis, promotes endogenous sy...

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Bibliographic Details
Main Authors: Shuxiang Wang, Arash Azarfar, Yajing Wang, Zhijun Cao, Shengli Li
Format: Article
Language:English
Published: BMC 2018-09-01
Series:Journal of Animal Science and Biotechnology
Subjects:
High-altitude pulmonary hypertension
Holstein heifers
N-carbamylglutamate
Tibet
Online Access:http://link.springer.com/article/10.1186/s40104-018-0277-6

Internet

http://link.springer.com/article/10.1186/s40104-018-0277-6

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