N-carbamylglutamate restores nitric oxide synthesis and attenuates high altitude-induced pulmonary hypertension in Holstein heifers ascended to high altitude
Abstract Background High-altitude pulmonary hypertension (HAPH) is a life-threating condition for animals in high altitude, and disturbance of endothelial nitric oxide (NO) synthesis contributes to its pathogenesis. N-carbamylglutamate (NCG), which enhances arginine synthesis, promotes endogenous sy...
Main Authors: | Shuxiang Wang, Arash Azarfar, Yajing Wang, Zhijun Cao, Shengli Li |
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Format: | Article |
Language: | English |
Published: |
BMC
2018-09-01
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Series: | Journal of Animal Science and Biotechnology |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s40104-018-0277-6 |
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