A Systematic Study of the Mechanism of Acacetin Against Sepsis Based on Network Pharmacology and Experimental Validation

A Systematic Study of the Mechanism of Acacetin Against Sepsis Based on Network Pharmacology and Experimental Validation

Sepsis is a dysregulated systemic response to infection, and no effective treatment options are available. Acacetin is a natural flavonoid found in various plants, including Sparganii rhizoma, Sargentodoxa cuneata and Patrinia scabiosifolia. Studies have revealed that acacetin potentially exerts ant...

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Bibliographic Details
Main Authors: Yuanshuo Ouyang, Yi Rong, Yanming Wang, Yanli Guo, Liya Shan, Xiushi Yu, Li Li, Junqiang Si, Xinzhi Li, Ketao Ma
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Pharmacology
Subjects:
sepsis
acacetin
network pharmacology
molecular docking
macrophage
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.683645/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.683645/full

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