Effect of Epstein-Barr Virus DNA on the Incidence and Severity of Arthritis in a Rheumatoid Arthritis Mouse Model

Effect of Epstein-Barr Virus DNA on the Incidence and Severity of Arthritis in a Rheumatoid Arthritis Mouse Model

ObjectiveWe recently demonstrated that EBV DNA is correlated with proinflammatory responses in mice and in rheumatoid arthritis (RA) patients; hence, we utilized an RA mouse model to examine whether EBV DNA enhances the risk and severity of arthritis and to assess its immunomodulatory effects.Method...

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Bibliographic Details
Main Authors: Sukayna Fadlallah, Hadi Hussein, Mary-Ann Jallad, Marwa Shehab, Abdo R. Jurjus, Ghassan M. Matar, Elias A. Rahal
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Immunology
Subjects:
rheumatoid arthritis
C57BL/6J mice
chicken collagen type II
Epstein-Barr virus DNA
proinflammatory responses
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.672752/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.672752/full

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