Regulatory T cell induction during Plasmodium chabaudi infection modifies the clinical course of experimental autoimmune encephalomyelitis.

BACKGROUND: Experimental autoimmune encephalomyelitis (EAE) is used as an animal model for human multiple sclerosis (MS), which is an inflammatory demyelinating autoimmune disease of the central nervous system characterized by activation of Th1 and/or Th17 cells. Human autoimmune diseases can be eit...

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Bibliographic Details
Main Authors: Alessandro S Farias, Rafael L Talaisys, Yara C Blanco, Stefanie C P Lopes, Ana Leda F Longhini, Fernando Pradella, Leonilda M B Santos, Fabio T M Costa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3064572?pdf=render