Resting-state network disruption and APOE genotype in Alzheimer's disease: a lagged functional connectivity study.

Resting-state network disruption and APOE genotype in Alzheimer's disease: a lagged functional connectivity study.

BACKGROUND: The apolipoprotein E epsilon 4 (APOE-4) is associated with a genetic vulnerability to Alzheimer's disease (AD) and with AD-related abnormalities in cortical rhythms. However, it is unclear whether APOE-4 is linked to a specific pattern of intrinsic functional disintegration of the b...

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Bibliographic Details
Main Authors: Leonides Canuet, Ivan Tellado, Veronica Couceiro, Carmen Fraile, Lucia Fernandez-Novoa, Ryouhei Ishii, Masatoshi Takeda, Ramon Cacabelos
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3457973?pdf=render

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http://europepmc.org/articles/PMC3457973?pdf=render

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